Jenna E. Kocsis, MD, Lead Resident, Department of Radiation Oncology, Cleveland Clinic Foundation, Cleveland, Ohio Sarah M. C. Sittenfeld, MD, Assistant Professor, Department of Radiation Oncology, University of Cincinnati, Cincinnati, Ohio Matthew C. Ward, MD, Adjunct Assistant Professor, Department of Radiation Oncology, Levine Cancer Institute, Atrium Health, Charlotte, North Carolina Rahul D. Tendulkar, MD FASTRO, Professor, Cleveland Clinic Lerner College of Medicine; Staff Physician, Department of Radiation Oncology, Cleveland Clinic Foundation, Cleveland, Ohio Gregory M. M. Videtic, MD, CM, FRCPC, Professor of Medicine, Cleveland Clinic Lerner College of Medicine; Staff Physician, Department of Radiation Oncology, Cleveland Clinic Foundation, Cleveland, Ohio
Description
Fully updated and expanded, Essentials of Clinical Radiation Oncology, 3rd Edition remains the most comprehensive and accessible clinical review for radiation oncologists, designed for optimal information retention and quick reference. Each chapter guides readers from clinical presentation to evidence-based decision-making, ensuring clarity and usability for both trainees and experienced practitioners. Chapters begin with "quick hit" summaries of each disease site, followed by high-yield coverage of epidemiology, risk factors, anatomy, pathology, genetics, screening, clinical presentation, workup, prognostic factors, staging, and medical management. Treatment paradigms outline the latest multidisciplinary standards of care including need-to-know radiation indications, prescription guidelines, and toxicities. To reinforce learning, each chapter concludes with an evidence-based question-and-answer section, summarizing key studies and practice-changing data that inform clinical decisions. Throughout the book, comprehensive tables consolidate critical information on staging, treatment options, patient selection, and clinical management for streamlined reference. Authored by expert clinicians and residents, this trusted clinical resource replicates the structure of a "house manual" making it an essential guide for radiation oncology residents, practicing radiation oncologists, and the broader radiation therapy team. Purchase includes digital access for use on most mobile devices or computers. Key Features: Logical organization - structured chapters present high-yield information for focused review Evidence-based information - presents clinical studies and data using an engaging, question and answer approach Essential Updates - reflects the latest research and clinical advancements in radiation oncology Quick Reference - includes comprehensive tables summarizing staging, treatment options, patient selection criteria, workup protocols, and prognostic factors by disease site Expanded Coverage - provides new clinical guidance about stereotactic radiosurgery for spinal tumors and head and neck cancers, altered fractionation, immunotherapy, radiotherapy for recurrent genitourinary cancers, pretransplant radiotherapy for leukemias, stereotactic radiotherapy for pediatric cases, treatment of oligometastatic disease, radiotherapy for benign conditions, and more.
Contributors Preface About the Format of This Book I. CENTRAL NERVOUS SYSTEM 1. Glioblastoma, IDH-Wildtype by Salem Alfaifi, Martin C. Tom, Jennifer S. Yu, and Samuel T. Chao 2. IDH-Mutant Gliomas: Grade 3 by Salem Alfaifi, Shireen Parsai, Jennifer S. Yu, Samuel T. Chao, and Martin C. Tom 3. Low Grade Gliomas by Adannia N. Ufondu, Erik M. Davies, Martin C. Tom, and Erin S. Murphy 4. Meningioma by Anirudh Bommireddy, Abigail L. Stockham, Martin C. Tom, and Jennifer S. Yu 5. Primary Central Nervous System Lymphoma by Sean M. Parker, Erin S. Murphy, and Samuel T. Chao 6. Pituitary Neuroendocrine Tumor by Bryn Myers, John H. Suh, and Praveen Pendyala 7. Trigeminal Neuralgia by Jana M. Kobeissi and Samuel T. Chao 8. Vestibular Schwannoma by Elizabeth E. Obi, Jeffrey A. Kittel, John H. Suh, and Praveen Pendyala 9. Uveal Melanoma by Bryn Myers, Gaurav Marwaha, John H. Suh, and Arun D. Singh 10. Spine Tumors by Elizabeth E. Obi, Sarah S. Kilic, Ehsan H. Balagamwala, and Samuel T. Chao II. HEAD AND NECK 11. Oropharynx Cancer by Zachary S. Mayo, Shireen Parsai, Aditya Juloori, and Jacob A. Miller 12. Oral Cavity Cancer by Adannia N. Ufondu, Kailin Yang, Bindu V. Manyam, and Neil M. Woody 13. Nasopharyngeal Cancer by Erik M. Davies, Christopher W. Fleming, Nikhil P. Joshi, and Jacob A. Miller 14. Laryngeal Cancer by David S. Buchberger, Aditya Juloori, and Shauna R. Campbell 15. Salivary Gland Tumors by Jenna E. Kocsis, Sarah S. Kilic, and Shlomo A. Koyfman 16. Carcinoma of Unknown Primary of the Head and Neck by Jana M. Kobeissi, Monica E. Shukla, Jeffrey A. Kittel, and Shauna R. Campbell 17. Postoperative Radiation for Head and Neck Cancer by Bryn M. Myers, Timothy D. Smile, Carryn M. Anderson, and Jacob A. Miller 18. Thyroid Cancer by David S. Buchberger, Nikhil P. Joshi, and Neil M. Woody 19. Sinonasal Tumors by Katherine R. Amarell, Timothy D. Smile, and Jacob A. Miller III. SKIN 20. Cutaneous Squamous Cell Carcinoma and Basal Cell Carcinoma by Bryn M. Myers, Timothy D. Smile, Nikhil P. Joshi, Neil M. Woody, and Shlomo A. Koyfman 21. Merkel Cell Carcinoma by Katherine R. Amarell, Ian Winter, Nikhil P. Joshi, and Shlomo A. Koyfman 22. Malignant Cutaneous Melanoma by Cole Billena, Sarah S. Kilic, Nikhil P. Joshi, and Neil M. Woody 23. Mycosis Fungoides by Anirudh Bommireddy, Matthew C. Ward, and Gregory M. M. Videtic IV. BREAST 24. Early-Stage Breast Cancer by Katherine R. Amarell, Kailin Yang, Rahul D. Tendulkar, and Chirag S. Shah 25. Locally Advanced Breast Cancer by Adannia N. Ufondu, Yvonne D. Pham, Rahul D. Tendulkar, and Chirag S. Shah 26. Ductal Carcinoma In Situ by Sean M. Parker, Timothy D. Smile, Rahul D. Tendulkar, and Chirag S. Shah 27. Recurrent Breast Cancer by Zachary S. Mayo and Chirag S. Shah V. THORACIC 28. Early-Stage Non-Small-Cell Lung Cancer by Salem Alfaifi, Gaurav Marwaha, Kevin L. Stephans, and Gregory M. M. Videtic 29. Stage III Non-Small-Cell Lung Cancer by Jenna E. Kocsis, Aditya Juloori, Kevin L. Stephans, and Gregory M. M. Videtic 30. Small-Cell Lung Cancer by Anirudh Bommireddy and Gregory M. M. Videtic 31. Mesothelioma by David S. Buchberger and Gregory M. M. Videtic 32. Thymoma by Cole Billena, Christopher W. Fleming, and Gregory M. M. Videtic VI. GASTROINTENTINAL 33. Esophageal Cancer by Sean Parker, Ehsan Balagamwala, and Gregory M. M. Videtic 34. Gastric Cancer by Ahmed Halima, Kevin L. Stephans, and Gregory M. M. Videtic 35. Hepatocellular Carcinoma by Erik M. Davies and Kevin L. Stephans 36. Pancreatic Adenocarcinoma by Ahmed Halima, James R. Broughman, Jacob A. Miller and Ehsan H. Balagamwala 37. Rectal Cancer by David S. Buchberger, Ian W. Winter, Jacob A. Miller, and Sudha R. Amarnath 38. Anal Cancer by Katherine R. Amarell, Jacob A. Miller, and Sudha R. Amarnath 39. Cholangiocarcinoma by Winston Vuong, Christopher W. Fleming, and Kevin L. Stephans VII. GENITOURINARY 40. Low-Risk Prostate Cancer by Zachary S. Mayo, Timothy D. Smile, Omar Y. Mian, and Rahul D. Tendulkar 41. Intermediate- and High-Risk Prostate Cancer by Cole Billena, Omar Y. Mian, and Rahul D. Tendulkar 42. Post-Prostatectomy Radiation Therapy by Sean M. Parker, James R. Broughman, Omar Y. Mian, and Rahul D. Tendulkar 43. Bladder Cancer by Winston Vuong, Erik M. Davies, Omar Y. Mian, and Rahul D. Tendulkar 44. Testicular Cancer by Zachary S. Mayo, Omar Y. Mian, and Rahul D. Tendulkar 45. Penile Cancer by Cole Billena, Rahul D. Tendulkar, and Omar Y. Mian 46. Urethral Cancer by Winston Vuong, Rahul D. Tendulkar, and Omar Y. Mian 47. Renal Cell Carcinoma by Salem Alfaifi, Omar Y. Mian, and Rahul D. Tendulkar VIII. GYNECOLOGIC 48. Cervical Cancer by Adannia N. Ufondu, Sheen Cherian, and Sudha R. Amarnath 49. Uterine Cancer: Endometrial Cancer and Uterine Sarcoma by David S. Buchberger, Sarah M. C. Sittenfeld, Sheen Cherian, and Sudha R. Amarnath 50. Vulvar Cancer by Jana M. Kobeissi, Sheen Cherian, and Sudha R. Amarnath 51. Vaginal Cancer by Erik M. Davies, Sheen Cherian, and Sudha R. Amarnath IX. HEMATOLOGIC 52. Adult Hodgkin's Lymphoma by Sean M. Parker, Matthew C. Ward and Sheen Cherian 53. Aggressive Non-Hodgkin's Lymphoma by Anirudh Bommireddy, Chirag S. Shah, and Sheen Cherian 54. Indolent Non-Hodgkin's Lymphoma by Jenna E. Kocsis, Aryavarta M. S. Kumar, and Christopher W. Fleming 55. Multiple Myeloma and Plasmacytoma by Anirudh Bommireddy, Kailin Yang and Sheen Cherian 56. Leukemia by Erik M. Davies, Erin S. Murphy, and Sheen Cherian X. SARCOMAS 57. Soft Tissue Sarcoma by Anirudh Bommireddy, Jacob G. Scott, and Shauna R. Campbell XI. PEDIATRIC 58. Medulloblastoma by Adannia N. Ufondu and Erin S. Murphy 59. Ependymoma by Adannia N. Ufondu, John H. Suh, and Erin S. Murphy 60. Brainstem Glioma by Jenna E. Kocsis, Jason W. D. Hearn, and John H. Suh 61. Craniopharyngioma by Zachary S. Mayo, Timothy D. Smile, and Martin C. Tom 62. Rhabdomyosarcoma by Cole Billena, Shauna R. Campbell, and Erin S. Murphy 63. Neuroblastoma by Salem Alfaifi, Praveen Pendyala, and Erin S. Murphy 64. Wilms Tumor by Salem Alfaifi, Praveen Pendyala, and Erin S. Murphy 65. Ewings Sarcoma by Jenna E. Kocsis, Shauna R. Campbell, and Erin S. Murphy 66. Pediatric Hodgkin's Lymphoma by Katherine R. Amarell, Sarah M. C. Sittenfeld, and Erin S. Murphy 67. Miscellaneous CNS Pediatric Tumors by Katherine R. Amarell, Praveen Pendyala, and Erin S. Murphy XII. METASTASES AND PALLIATIVE RADIOTHERAPY 68. Brain Metastases by Winston Vuong, Martin C. Tom, and John H. Suh 69. Bone and Spine Metastasis by Sean M. Parker, Ehsan H. Balagamwala, Samuel T. Chao, and Andrew D. Vassil 70. Malignant Spinal Cord Compression by Cole Billena and Samuel T. Chao 71. Superior Vena Cava Syndrome by Anirudh Bommireddy and Gregory M. M. Videtic 72. Palliative Radiotherapy by David S. Buchberger, Matthew C. Ward, and Andrew Vassil 73. Oligometastatic Disease by Salem Alfaifi, Ian W. Winter, Martin C. Tom, Rahul D. Tendulkar, and Ehsan H. Balagamwala XIII. BENIGN DISEASES 74. Radiation Therapy for Benign Diseases by Ahmed Halima, Rahul D. Tendulkar, and Chirag S. Shah Abbreviations Index